help  | about  | cite  | software

Gene : ATG5 Homo sapiens

Name  ? autophagy related 5 Cytological Location  6q21
Brief Description  autophagy related 5
Description  The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
  • synonyms:
  • ATG5 autophagy related 5 homolog (S. cerevisiae),
  • ASP,
  • ATG5,
  • OTTHUMG00000016193,
  • ASP,
  • uc003prf.4,
  • APG5 autophagy 5-like (S. cerevisiae),
  • APG5,
  • hAPG5,
  • NM_004849,
  • hAPG5,
  • APG5-LIKE,
  • HGNC:589,
  • APG5L,
  • APG5 (autophagy 5, S. cerevisiae)-like,
  • Y11588,
  • APG5,
  • APG5L,
  • SCAR25
  • identifiers:
  • 9474,
  • ENSG00000057663,
  • ATG5

Genome feature

Region: gene ? Length: 141345  
Location: 6:106184476-106325820 reverse strand Cyto location: 6q21


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Gene --> Orthologues

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

509 SN Ps

5 Cross References

20 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results