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Gene : ATG5 Homo sapiens

Name  ? autophagy related 5 Cytological Location  6q21
Brief Description  autophagy related 5
Description  The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
  • synonyms:
  • NM_004849,
  • APG5 (autophagy 5, S. cerevisiae)-like,
  • ATG5 autophagy related 5 homolog (S. cerevisiae),
  • SCAR25,
  • ASP,
  • hAPG5,
  • hAPG5,
  • APG5L,
  • APG5 autophagy 5-like (S. cerevisiae),
  • APG5,
  • HGNC:589,
  • ASP,
  • ATG5,
  • OTTHUMG00000016193,
  • APG5-LIKE,
  • APG5L,
  • uc003prf.4,
  • Y11588,
  • APG5
  • identifiers:
  • 9474,
  • ENSG00000057663,
  • ATG5

Genome feature

Region: gene ? Length: 141314  
Location: 6:106184476-106325789 reverse strand Cyto location: 6q21

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

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Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



509 SN Ps

5 Cross References

19 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results