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Gene : CD36 Homo sapiens

Name  ? CD36 molecule Cytological Location  7q21.11
Brief Description  CD36 molecule
Description  The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]
  • synonyms:
  • GPIV,
  • PASIV,
  • CD36 antigen (collagen type I receptor, thrombospondin receptor),
  • uc003uhc.4,
  • GP4,
  • FAT,
  • GP3B,
  • CD36,
  • GP4,
  • CHDS7,
  • HGNC:1663,
  • SCARB3,
  • GP3B,
  • FAT,
  • OTTHUMG00000155383,
  • BDPLT10,
  • Z32770,
  • NM_001001547,
  • CD36 molecule (thrombospondin receptor),
  • SCARB3,
  • GPIV
  • identifiers:
  • 948,
  • ENSG00000135218,
  • CD36

Genome feature

Region: gene ? Length: 77071  
Location: 7:80602207-80679277 Cyto location: 7q21.11


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47 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

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Disease

3 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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47 Pathways

3753 SN Ps

5 Cross References

20 Data Sets

21 Homologues

0 Located Features

97 Rna Seq Results