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Gene : NPEPPS Homo sapiens

Name  ? aminopeptidase puromycin sensitive Cytological Location  17q21.32
Brief Description  aminopeptidase puromycin sensitive
Description  This gene encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle. [provided by RefSeq, Jul 2008]
  • synonyms:
  • MP100,
  • metalloproteinase MP100,
  • HGNC:7900,
  • MP100,
  • uc002ilr.5,
  • NM_006310,
  • AAP-S,
  • puromycin-sensitive aminopeptidase,
  • OTTHUMG00000165471,
  • Y07701,
  • PSA,
  • PSA
  • identifiers:
  • 9520,
  • ENSG00000141279,

Genome feature

Region: gene ? Length: 100344  
Location: 17:47522933-47623276 Cyto location: 17q21.32

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Proteins.


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3740 SNPs

5 Cross References

17 Data Sets

26 Homologues

0 Located Features

97 Rna Seq Results