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Gene : BCAR1 Homo sapiens

Name  ? BCAR1 scaffold protein, Cas family member Cytological Location  16q23.1
Brief Description  BCAR1 scaffold protein, Cas family member
Description  The protein encoded by this gene is a member of the Crk-associated substrate (CAS) family of scaffold proteins, characterized by the presence of multiple protein-protein interaction domains and many serine and tyrosine phosphorylation sites. The encoded protein contains a Src-homology 3 (SH3) domain, a proline-rich domain, a substrate domain which contains 15 repeat of the YxxP consensus phosphorylation motif for Src family kinases, a serine-rich domain, and a bipartite Src-binding domain, which can bind both SH2 and SH3 domains. This adaptor protein functions in multiple cellular pathways, including in cell motility, apoptosis and cell cycle control. Dysregulation of this gene can have a wide range of effects, affecting different pathways, including cardiac development, vascular smooth muscle cells, liver and kidney function, endothelial migration, and cancer. [provided by RefSeq, Sep 2017]
  • synonyms:
  • BCAR1, Cas family scaffolding protein,
  • HGNC:971,
  • CAS,
  • CAS,
  • BCAR1, Cas family scaffold protein,
  • Crk-associated substrate,
  • CRKAS,
  • breast cancer anti-estrogen resistance 1,
  • CASS1,
  • Crkas,
  • P130Cas,
  • AJ242987,
  • NM_014567,
  • uc002fdv.4,
  • Cas scaffolding protein family member 1,
  • BCAR1,
  • CAS1,
  • P130Cas,
  • OTTHUMG00000137604,
  • CASS1
  • identifiers:
  • 9564,
  • ENSG00000050820,
  • BCAR1

Genome feature

Region: gene ? Length: 39827  
Location: 16:75228181-75268007 reverse strand Cyto location: 16q23.1


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3753 SN Ps

5 Cross References

17 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results