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Gene : BABAM2 Homo sapiens

Name  ? BRISC and BRCA1 A complex member 2 Cytological Location  2p23.2
Brief Description  BRISC and BRCA1 A complex member 2
Description  This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer. [provided by RefSeq, Jun 2016]
  • synonyms:
  • HGNC:1106,
  • BRCC4,
  • BRCC4,
  • BRCC45,
  • uc002rlu.4,
  • brain and reproductive organ-expressed (TNFRSF1A modulator),
  • BRE,
  • NM_001261840,
  • OTTHUMG00000097831,
  • BRCA1/BRCA2-containing complex, subunit 4,
  • BRCC45,
  • BABAM2,
  • AF015767,
  • BRE
  • identifiers:
  • 9577,
  • ENSG00000158019,
  • BABAM2

Genome feature

Region: gene ? Length: 450193  
Location: 2:27888709-28338901 Cyto location: 2p23.2


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Gene --> Orthologues

Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

232 SN Ps

5 Cross References

16 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results