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Gene : CD40LG Homo sapiens

Name  ? CD40 ligand Cytological Location  Xq26.3
Brief Description  CD40 ligand
Description  The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008]
  • synonyms:
  • IMD3,
  • TNFSF5,
  • CD40L,
  • T-B cell-activating molecule,
  • IMD3,
  • gp39,
  • CD154,
  • CD154,
  • TRAP,
  • CD40 antigen ligand,
  • OTTHUMG00000022512,
  • HIGM1,
  • HGNC:11935,
  • tumor necrosis factor (ligand) superfamily, member 5 (hyper-IgM syndrome),
  • TNF-related activation protein,
  • TNFSF5,
  • hCD40L,
  • X67878,
  • NM_000074,
  • gp39,
  • IGM,
  • hyper-IgM syndrome,
  • tumor necrosis factor (ligand) superfamily member 5,
  • CD40L,
  • hCD40L,
  • T-BAM,
  • HIGM1,
  • uc004faa.4,
  • TRAP,
  • CD40LG
  • identifiers:
  • 959,
  • ENSG00000102245,
  • CD40LG

Genome feature

Region: gene ? Length: 12233  
Location: X:136648158-136660390 Cyto location: Xq26.3


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

16 SN Ps

5 Cross References

19 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results