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Gene : CD44 Homo sapiens

Name  ? CD44 molecule (Indian blood group) Cytological Location  11p13
Brief Description  CD44 molecule (Indian blood group)
Description  The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
  • synonyms:
  • MDU2,
  • MDU2,
  • IN,
  • hematopoietic cell E- and L-selectin ligand,
  • CD44 antigen (homing function and Indian blood group system),
  • IN,
  • CDW44,
  • M59040,
  • Pgp1,
  • NM_000610,
  • CSPG8,
  • MIC4,
  • CSPG8,
  • Pgp1,
  • CD44,
  • HUTCH-I,
  • HCELL,
  • chondroitin sulfate proteoglycan 8,
  • HGNC:1681,
  • MC56,
  • LHR,
  • HCELL,
  • uc001mvu.4,
  • OTTHUMG00000044388,
  • MC56,
  • MDU3,
  • MDU3,
  • MIC4,
  • ECMR-III,
  • CD44R
  • identifiers:
  • 960,
  • ENSG00000026508,
  • CD44

Genome feature

Region: gene ? Length: 93235  
Location: 11:35139168-35232402 Cyto location: 11p13


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Disease

1 Diseases

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977 SN Ps

5 Cross References

19 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results