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Gene : AATK Homo sapiens

Name  ? apoptosis associated tyrosine kinase Cytological Location  17q25.3
Brief Description  apoptosis associated tyrosine kinase
Description  The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
  • synonyms:
  • lemur tyrosine kinase 1,
  • AATYK1,
  • NM_004920,
  • PPP1R77,
  • AATYK1,
  • LMR1,
  • LMR1,
  • protein phosphatase 1, regulatory subunit 77,
  • KIAA0641,
  • LMTK1,
  • AATYK,
  • AB014541,
  • PPP1R77,
  • p35BP,
  • HGNC:21,
  • uc010dia.4,
  • OTTHUMG00000132717,
  • AATYK,
  • LMTK1,
  • AATK
  • identifiers:
  • 9625,
  • ENSG00000181409,
  • AATK

Genome feature

Region: gene ? Length: 48927  
Location: 17:81117295-81166221 reverse strand Cyto location: 17q25.3

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

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Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

702 SN Ps

5 Cross References

16 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results