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Gene : CD53 Homo sapiens

Name  ? CD53 molecule Cytological Location  1p13.3
Brief Description  CD53 molecule
Description  The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
  • synonyms:
  • TSPAN25,
  • HGNC:1686,
  • BC040693,
  • CD53,
  • NM_000560,
  • OTTHUMG00000048020,
  • CD53 antigen,
  • uc001dzx.4,
  • MOX44,
  • TSPAN25,
  • MOX44
  • identifiers:
  • 963,
  • ENSG00000143119,
  • CD53

Genome feature

Region: gene ? Length: 28770  
Location: 1:110871167-110899936 Cyto location: 1p13.3


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

571 SN Ps

5 Cross References

16 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results