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Gene : CLCA2 Homo sapiens

Name  ? chloride channel accessory 2 Cytological Location  1p22.3
Brief Description  chloride channel accessory 2
Description  This gene encodes a member of the calcium-activated chloride channel regulator (CLCR) family of proteins. Members of this family regulate the transport of chloride across the plasma membrane. The encoded protein is autoproteolytically processed to generate N- and C- terminal fragments. Expression of this gene is upregulated by the tumor suppressor protein p53 in response to DNA damage. In breast cancer, expression of this gene is downregulated and the encoded protein may inhibit migration and invasion while promoting mesenchymal-to-epithelial transition in cancer cell lines. [provided by RefSeq, Sep 2016]
  • synonyms:
  • chloride channel regulator 2,
  • chloride channel, calcium activated, family member 2,
  • OTTHUMG00000010256,
  • CACC3,
  • CACC,
  • NM_006536,
  • HGNC:2016,
  • CaCC-3,
  • CLCRG2,
  • CLCA2,
  • CLCRG2,
  • uc001dlr.5
  • identifiers:
  • 9635,
  • ENSG00000137975,
  • CLCA2

Genome feature

Region: gene ? Length: 32410  
Location: 1:86424144-86456553 Cyto location: 1p22.3


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Proteins

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Disease

0 Diseases

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Expression

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Other

3753 SN Ps

5 Cross References

18 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results