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Gene : CD63 Homo sapiens

Name  ? CD63 molecule Cytological Location  12q13.2
Brief Description  CD63 molecule
Description  The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
  • synonyms:
  • MLA1,
  • TSPAN30,
  • MLA1,
  • OTTHUMG00000170454,
  • TSPAN30,
  • ME491,
  • NM_001257389,
  • uc031qhx.2,
  • CD63,
  • M58485,
  • LAMP-3,
  • OMA81H,
  • ME491,
  • CD63 antigen (melanoma 1 antigen),
  • HGNC:1692
  • identifiers:
  • 967,
  • ENSG00000135404,
  • CD63

Genome feature

Region: gene ? Length: 4351  
Location: 12:55725323-55729673 reverse strand Cyto location: 12q13.2


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Proteins

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SNPs

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Disease

0 Diseases

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Gene -> HPO annotation (Human Phenotype Ontology)

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Expression

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Other

201 SN Ps

5 Cross References

18 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results