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Gene : CD68 Homo sapiens

Name  ? CD68 molecule Cytological Location  17p13.1
Brief Description  CD68 molecule
Description  This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
  • synonyms:
  • SCARD1,
  • scavenger receptor class D, member 1,
  • CD68,
  • HGNC:1693,
  • CD68 antigen,
  • SCARD1,
  • macrosialin,
  • GP110,
  • macrophage antigen CD68,
  • NM_001251,
  • GP110,
  • S57235,
  • LAMP4,
  • uc002ghv.4,
  • LAMP4,
  • DKFZp686M18236,
  • OTTHUMG00000108146
  • identifiers:
  • 968,
  • ENSG00000129226,
  • CD68

Genome feature

Region: gene ? Length: 2474  
Location: 17:7579638-7582111 Cyto location: 17p13.1

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265 SN Ps

5 Cross References

16 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results