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Gene : CD70 Homo sapiens

Name  ? CD70 molecule Cytological Location  19p13.3
Brief Description  CD70 molecule
Description  The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]
  • synonyms:
  • OTTHUMG00000181834,
  • TNFSF7,
  • TNFSF7,
  • L08096,
  • CD27LG,
  • CD27L,
  • CD27L,
  • CD27LG,
  • LPFS3,
  • uc002mfi.3,
  • HGNC:11937,
  • tumor necrosis factor (ligand) superfamily, member 7,
  • NM_001252,
  • CD70,
  • TNLG8A,
  • CD27-L
  • identifiers:
  • 970,
  • ENSG00000125726,
  • CD70

Genome feature

Region: gene ? Length: 9503  
Location: 19:6581648-6591150 reverse strand Cyto location: 19p13.3

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1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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126 SNPs

5 Cross References

17 Data Sets

2 Homologues

0 Located Features

97 Rna Seq Results