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Gene : DOCK4 Homo sapiens

Name  ? dedicator of cytokinesis 4 Cytological Location  7q31.1
Brief Description  dedicator of cytokinesis 4
Description  This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized. [provided by RefSeq, Jul 2008]
  • synonyms:
  • DOCK4,
  • uc003vfx.4,
  • HGNC:19192,
  • KIAA0716,
  • OTTHUMG00000155077,
  • FLJ34238,
  • NM_014705
  • identifiers:
  • 9732,
  • ENSG00000128512,
  • DOCK4

Genome feature

Region: gene ? Length: 480290  
Location: 7:111726110-112206399 reverse strand Cyto location: 7q31.1


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Proteins

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SNPs

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Disease

0 Diseases

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Expression

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412 SN Ps

5 Cross References

16 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results