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Gene : HDAC4 Homo sapiens

Name  ? histone deacetylase 4 Cytological Location  2q37.3
Brief Description  histone deacetylase 4
Description  Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]
  • synonyms:
  • AB006626,
  • OTTHUMG00000133344,
  • HD4,
  • AHO3,
  • HDAC-4,
  • NM_006037,
  • HDAC-4,
  • brachydactyly-mental retardation syndrome,
  • KIAA0288,
  • HGNC:14063,
  • HD4,
  • HA6116,
  • HDACA,
  • HDAC-A,
  • HDACA,
  • HDAC-A,
  • HDAC4,
  • HA6116,
  • BDMR,
  • uc002vyk.4,
  • BDMR
  • identifiers:
  • 9759,
  • ENSG00000068024,
  • HDAC4

Genome feature

Region: gene ? Length: 353482  
Location: 2:239048168-239401649 reverse strand Cyto location: 2q37.3


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Disease

0 Diseases

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Other

390 SN Ps

5 Cross References

17 Data Sets

9 Homologues

0 Located Features

97 Rna Seq Results