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Gene : CDK1 Homo sapiens

Name  ? cyclin dependent kinase 1 Cytological Location  10q21.2
Brief Description  cyclin dependent kinase 1
Description  The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • synonyms:
  • CDK1,
  • P34CDC2,
  • HGNC:1722,
  • NM_001786,
  • uc001jld.3,
  • cell division cycle 2, G1 to S and G2 to M,
  • CDC2,
  • BC014563,
  • CDC2,
  • CDC28A,
  • OTTHUMG00000018290,
  • CDC28A
  • identifiers:
  • 983,
  • ENSG00000170312,
  • CDK1

Genome feature

Region: gene ? Length: 16522  
Location: 10:60778331-60794852 Cyto location: 10q21.2


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75 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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Other

75 Pathways

306 SN Ps

5 Cross References

17 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results