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Gene : CDK11B Homo sapiens

Name  ? cyclin dependent kinase 11B Cytological Location  1p36.33
Brief Description  cyclin dependent kinase 11B
Description  This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
  • synonyms:
  • p58CLK-1,
  • CDK11-p110,
  • CDK11B,
  • CDK11-p46,
  • CLK-1,
  • cell division cycle 2-like 1 (PITSLRE proteins),
  • PK58,
  • CDC2L1,
  • p58,
  • HGNC:1729,
  • p58CDC2L1,
  • AK000081,
  • CDK11-p58,
  • CDK11,
  • CDK11-p46,
  • NM_001787,
  • uc031tml.2,
  • CDK11-p58,
  • OTTHUMG00000078638,
  • CDC2L1,
  • CDK11-p110
  • identifiers:
  • 984,
  • ENSG00000248333,
  • CDK11B

Genome feature

Region: gene ? Length: 24395  
Location: 1:1635225-1659619 reverse strand Cyto location: 1p36.33

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3740 SNPs

5 Cross References

16 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results