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Gene : GAB2 Homo sapiens

Name  ? GRB2 associated binding protein 2 Cytological Location  11q14.1
Brief Description  GRB2 associated binding protein 2
Description  This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009]
  • synonyms:
  • OTTHUMG00000166673,
  • AB011143,
  • uc001ozh.4,
  • GAB2,
  • KIAA0571,
  • HGNC:14458,
  • NM_080491,
  • Grb2-associated binder 2
  • identifiers:
  • 9846,
  • ENSG00000033327,
  • GAB2

Genome feature

Region: gene ? Length: 202531  
Location: 11:78215290-78417820 reverse strand Cyto location: 11q14.1


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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Other

3753 SN Ps

5 Cross References

18 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results