Name
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adaptor related protein complex 5 subunit zeta 1 | Cytological Location | 7p22.1 |
Brief Description | adaptor related protein complex 5 subunit zeta 1 |
Description | This gene was identified by genome-wide screen for genes involved in homologous recombination DNA double-strand break repair (HR-DSBR). The encoded protein was found in a complex with other proteins that have a role in HR-DSBR. Knockdown of this gene reduced homologous recombination, and mutations in this gene were found in patients with spastic paraplegia. It was concluded that this gene likely encodes a helicase (PMID:20613862). [provided by RefSeq, Jan 2011] |