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Gene : ARNT2 Homo sapiens

Name  ? aryl hydrocarbon receptor nuclear translocator 2 Cytological Location  15q25.1
Brief Description  aryl hydrocarbon receptor nuclear translocator 2
Description  This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq, Dec 2013]
  • synonyms:
  • NM_014862,
  • OTTHUMG00000165478,
  • WEDAS,
  • KIAA0307,
  • AB002305,
  • HGNC:16876,
  • bHLHe1,
  • bHLHe1,
  • uc002bfr.4,
  • ARNT2
  • identifiers:
  • 9915,
  • ENSG00000172379,
  • ARNT2

Genome feature

Region: gene ? Length: 193552  
Location: 15:80404382-80597933 Cyto location: 15q25.1

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1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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3740 SNPs

5 Cross References

19 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results