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Gene : CDC42 Homo sapiens

Name  ? cell division cycle 42 Cytological Location  1p36.12
Brief Description  cell division cycle 42
Description  The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013]
  • synonyms:
  • G25K,
  • CDC42Hs,
  • OTTHUMG00000002753,
  • CDC42Hs,
  • cell division cycle 42 (GTP-binding protein, 25kD),
  • G25K,
  • cell division cycle 42 (GTP binding protein, 25kDa),
  • CDC42,
  • BC018266,
  • NM_001791,
  • HGNC:1736,
  • GTP binding protein, 25kDa,
  • TKS,
  • uc057ddl.1
  • identifiers:
  • 998,
  • ENSG00000070831,
  • CDC42

Genome feature

Region: gene ? Length: 48652  
Location: 1:22052709-22101360 Cyto location: 1p36.12


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74 Pathways

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Disease

1 Diseases

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74 Pathways

3753 SN Ps

5 Cross References

20 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results