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Gene : CASP8AP2 Homo sapiens

Name  ? caspase 8 associated protein 2 Cytological Location  6q15
Brief Description  caspase 8 associated protein 2
Description  This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Nov 2008]
  • synonyms:
  • NM_001137667,
  • FLICE-associated huge protein,
  • KIAA1315,
  • FLASH,
  • RIP25,
  • AB037736,
  • OTTHUMG00000015212,
  • CED-4,
  • RIP25,
  • FLASH,
  • CASP8 associated protein 2,
  • FLJ11208,
  • uc063qcj.1,
  • CED-4,
  • CASP8AP2,
  • HGNC:1510
  • identifiers:
  • 9994,
  • ENSG00000118412,
  • CASP8AP2

Genome feature

Region: gene ? Length: 44557  
Location: 6:89829880-89874436 Cyto location: 6q15

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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474 SN Ps

5 Cross References

13 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results