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Gene : ADAMTS3 Homo sapiens

Name  ? ADAM metallopeptidase with thrombospondin type 1 motif 3 Cytological Location  4q13.3
Brief Description  ADAM metallopeptidase with thrombospondin type 1 motif 3
Description  This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease, a member of the procollagen aminopropeptidase subfamily of proteins, may play a role in the processing of type II fibrillar collagen in articular cartilage. [provided by RefSeq, Feb 2016]
  • synonyms:
  • ADAMTS-4,
  • KIAA0366,
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3,
  • ADAMTS3,
  • NM_014243,
  • ADAMTS-4,
  • HKLLS3,
  • AB002364,
  • OTTHUMG00000129912,
  • HGNC:219,
  • uc003hgk.2
  • identifiers:
  • 9508,
  • ENSG00000156140,

Genome feature

Region: gene ? Length: 288253  
Location: 4:72280969-72569221 reverse strand Cyto location: 4q13.3

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1 Diseases

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3740 SNPs

5 Cross References

19 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results