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Gene : CD81 Homo sapiens

Name  ? CD81 molecule Cytological Location  11p15.5
Brief Description  CD81 molecule
Description  The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
  • synonyms:
  • TSPAN28,
  • OTTHUMG00000009892,
  • NM_004356,
  • TSPAN28,
  • uc001lwf.2,
  • CD81 antigen (target of antiproliferative antibody 1),
  • HGNC:1701,
  • CVID6,
  • CD81,
  • TAPA-1,
  • S5.7,
  • TAPA1,
  • TAPA1
  • identifiers:
  • 975,
  • ENSG00000110651,
  • CD81

Genome feature

Region: gene ? Length: 21223  
Location: 11:2376180-2397402 Cyto location: 11p15.5

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



825 SNPs

5 Cross References

18 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results