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Gene : EZH2 Homo sapiens

Name  ? enhancer of zeste 2 polycomb repressive complex 2 subunit Cytological Location  7q36.1
Brief Description  enhancer of zeste 2 polycomb repressive complex 2 subunit
Description  This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
  • synonyms:
  • KMT6,
  • NM_004456,
  • EZH1,
  • EZH2,
  • enhancer of zeste (Drosophila) homolog 2,
  • ENX-1,
  • WVS2,
  • ENX1,
  • enhancer of zeste homolog 2 (Drosophila),
  • HGNC:3527,
  • OTTHUMG00000158973,
  • uc003wfb.3,
  • KMT6A,
  • WVS,
  • KMT6A,
  • EZH2b,
  • KMT6,
  • ENX-1
  • identifiers:
  • 2146,
  • ENSG00000106462,
  • EZH2

Genome feature

Region: gene ? Length: 76971  
Location: 7:148807374-148884344 reverse strand Cyto location: 7q36.1

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Gene -> HPO annotation (Human Phenotype Ontology)

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1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



267 SN Ps

5 Cross References

19 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results