help  | about  | cite  | software

Gene : GCG Homo sapiens

Name  ? glucagon Cytological Location  2q24.2
Brief Description  glucagon
Description  The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008]
  • synonyms:
  • GLP-1,
  • GLP-1,
  • GRPP,
  • HGNC:4191,
  • GLP2,
  • NM_002054,
  • GLP1,
  • GLP1,
  • glicentin-related polypeptide,
  • GCG,
  • preproglucagon,
  • glucagon-like peptide 2,
  • glucagon-like peptide 1,
  • GRPP,
  • OTTHUMG00000153892,
  • uc002ucc.5,
  • GLP2
  • identifiers:
  • 2641,
  • ENSG00000115263,
  • GCG

Genome feature

Region: gene ? Length: 9366  
Location: 2:162142882-162152247 reverse strand Cyto location: 2q24.2

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 SN Ps

5 Cross References

15 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results