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Gene : ITIH4 Homo sapiens

Name  ? inter-alpha-trypsin inhibitor heavy chain 4 Cytological Location  3p21.1
Brief Description  inter-alpha-trypsin inhibitor heavy chain 4
Description  The protein encoded by this gene is secreted into the blood, where it is cleaved by plasma kallikrein into two smaller forms. Expression of this gene has been detected only in liver, and it seems to be upregulated during surgical trauma. This gene is part of a cluster of similar genes on chromosome 3. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
  • synonyms:
  • inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein),
  • NM_002218,
  • GP120,
  • PK120,
  • ITI-HC4,
  • D38535,
  • plasma Kallikrein-sensitive glycoprotein,
  • ITIHL1,
  • ITIH4,
  • H4P,
  • OTTHUMG00000159023,
  • H4P,
  • ITIHL1,
  • inter-alpha-trypsin inhibitor heavy chain family, member 4,
  • HGNC:6169,
  • IHRP,
  • PK-120,
  • uc003dfz.4,
  • IHRP
  • identifiers:
  • 3700,
  • ENSG00000055955,
  • ITIH4

Genome feature

Region: gene ? Length: 17740  
Location: 3:52812962-52830701 reverse strand Cyto location: 3p21.1

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



26586 SN Ps

5 Cross References

15 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results