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Gene : FBXO5 Homo sapiens

Name  ? F-box protein 5 Cytological Location  6q25.2
Brief Description  F-box protein 5
Description  This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Dec 2008]
  • synonyms:
  • Fbxo31,
  • FBX5,
  • EMI1,
  • OTTHUMG00000015854,
  • Fbxo31,
  • FBX5,
  • EMI1,
  • uc003qpg.4,
  • NM_001142522,
  • F-box only protein 5,
  • FBXO5,
  • HGNC:13584,
  • AF129535
  • identifiers:
  • 26271,
  • ENSG00000112029,
  • FBXO5

Genome feature

Region: gene ? Length: 13045  
Location: 6:152970535-152983579 reverse strand Cyto location: 6q25.2

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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41 SN Ps

5 Cross References

16 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results