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Gene : CDS1 Homo sapiens

Name  ? CDP-diacylglycerol synthase 1 Cytological Location  4q21.23
Brief Description  CDP-diacylglycerol synthase 1
Description  Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13. [provided by RefSeq, Jul 2008]
  • synonyms:
  • phosphatidate cytidylyltransferase,
  • OTTHUMG00000130428,
  • NM_001263,
  • uc011ccv.3,
  • CDS1,
  • CDS 1,
  • U65887,
  • HGNC:1800
  • identifiers:
  • 1040,
  • ENSG00000163624,
  • CDS1

Genome feature

Region: gene ? Length: 68404  
Location: 4:84582931-84651334 Cyto location: 4q21.23


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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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Other

374 SN Ps

5 Cross References

17 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results