help  | about  | cite  | software

Gene : CNOT7 Homo sapiens

Name  ? CCR4-NOT transcription complex subunit 7 Cytological Location  8p22
Brief Description  CCR4-NOT transcription complex subunit 7
Description  The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Apr 2016]
  • synonyms:
  • HGNC:14101,
  • CAF-1,
  • CNOT7,
  • OTTHUMG00000096971,
  • uc003wxg.2,
  • NM_013354,
  • CAF1,
  • L46722,
  • CAF1,
  • hCAF-1,
  • BTG1 binding factor 1,
  • CCR4-NOT transcription complex, subunit 7,
  • Caf1a
  • identifiers:
  • 29883,
  • ENSG00000198791,
  • CNOT7

Genome feature

Region: gene ? Length: 24929  
Location: 8:17221981-17246909 reverse strand Cyto location: 8p22


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

3753 SN Ps

5 Cross References

16 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results