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Gene : CCL2 Homo sapiens

Name  ? C-C motif chemokine ligand 2 Cytological Location  17q12
Brief Description  C-C motif chemokine ligand 2
Description  This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq, Jul 2013]
  • synonyms:
  • SMC-CF,
  • NM_002982,
  • MCP1,
  • SCYA2,
  • HSMCR30,
  • MCP-1,
  • chemokine (C-C motif) ligand 2,
  • monocyte chemoattractant protein-1,
  • monocyte secretory protein JE,
  • MCP1,
  • SMC-CF,
  • BC009716,
  • SCYA2,
  • MCAF,
  • GDCF-2,
  • HC11,
  • monocyte chemotactic and activating factor,
  • MGC9434,
  • GDCF-2,
  • monocyte chemotactic protein 1, homologous to mouse Sig-je,
  • MCP-1,
  • OTTHUMG00000132887,
  • HC11,
  • CCL2,
  • uc002hhy.4,
  • small inducible cytokine subfamily A (Cys-Cys), member 2,
  • HGNC:10618,
  • MCAF,
  • small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)
  • identifiers:
  • 6347,
  • ENSG00000108691,
  • CCL2

Genome feature

Region: gene ? Length: 1919  
Location: 17:34255285-34257203 Cyto location: 17q12


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Proteins

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Disease

3 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Expression

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Other

248 SN Ps

5 Cross References

19 Data Sets

14 Homologues

0 Located Features

97 Rna Seq Results