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Gene : GANAB Homo sapiens

Name  ? glucosidase II alpha subunit Cytological Location  11q12.3
Brief Description  glucosidase II alpha subunit
Description  This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease. [provided by RefSeq, Jul 2016]
  • synonyms:
  • GIIA,
  • PKD3,
  • G2AN,
  • NM_198334,
  • GLUII,
  • glucosidase, alpha; neutral AB,
  • uc001nub.5,
  • GANAB,
  • OTTHUMG00000167696,
  • KIAA0088,
  • neutral alpha-glucosidase AB,
  • G2AN,
  • AF144074,
  • GluII,
  • HGNC:4138,
  • GIIA
  • identifiers:
  • 23193,
  • ENSG00000089597,

Genome feature

Region: gene ? Length: 21901  
Location: 11:62624826-62646726 reverse strand Cyto location: 11q12.3

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1 Diseases

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630 SN Ps

5 Cross References

20 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results