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Gene : DNAJC2 Homo sapiens

Name  ? DnaJ heat shock protein family (Hsp40) member C2 Cytological Location  7q22.1
Brief Description  DnaJ heat shock protein family (Hsp40) member C2
Description  This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq, Jul 2008]
  • synonyms:
  • ZUO1,
  • DnaJ (Hsp40) homolog, subfamily C, member 2,
  • MPP11,
  • MPHOSPH11,
  • HGNC:13192,
  • ZRF1,
  • MPHOSPH11,
  • X98260,
  • ZUO1,
  • DNAJC2,
  • uc003vbo.4,
  • ZRF1,
  • NM_001129887,
  • zuotin,
  • OTTHUMG00000157202,
  • zuotin related factor 1,
  • MPP11
  • identifiers:
  • 27000,
  • ENSG00000105821,
  • DNAJC2

Genome feature

Region: gene ? Length: 32585  
Location: 7:103312289-103344873 reverse strand Cyto location: 7q22.1

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

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Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



880 SN Ps

5 Cross References

15 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results