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Gene : ACE Homo sapiens

Name  ? angiotensin I converting enzyme Cytological Location  17q23.3
Brief Description  angiotensin I converting enzyme
Description  This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010]
  • synonyms:
  • angiotensin I converting enzyme (peptidyl-dipeptidase A) 1,
  • CD143,
  • HGNC:2707,
  • CD143,
  • J04144,
  • uc002jau.4,
  • OTTHUMG00000154927,
  • DCP1,
  • DCP,
  • ACE1,
  • DCP1,
  • ACE,
  • NM_000789,
  • peptidyl-dipeptidase A,
  • ACE1
  • identifiers:
  • 1636,
  • ENSG00000159640,
  • ACE

Genome feature

Region: gene ? Length: 21313  
Location: 17:63477061-63498373 Cyto location: 17q23.3

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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3 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3753 SN Ps

5 Cross References

20 Data Sets

10 Homologues

0 Located Features

97 Rna Seq Results