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Gene : DERL3 Homo sapiens

Name  ? derlin 3 Cytological Location  22q11.23
Brief Description  derlin 3
Description  The protein encoded by this gene belongs to the derlin family, and resides in the endoplasmic reticulum (ER). Proteins that are unfolded or misfolded in the ER must be refolded or degraded to maintain the homeostasis of the ER. This protein appears to be involved in the degradation of misfolded glycoproteins in the ER. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008]
  • synonyms:
  • IZP6,
  • C22orf14,
  • derlin-3,
  • uc002zyh.4,
  • LLN2,
  • chromosome 22 open reading frame 14,
  • DERL3,
  • Der1-like domain family, member 3,
  • HGNC:14236,
  • C22orf14,
  • derlin-3,
  • MGC71803,
  • OTTHUMG00000150743,
  • IZP6,
  • NM_198440,
  • AB049213,
  • FLJ43842
  • identifiers:
  • 91319,
  • ENSG00000099958,
  • DERL3

Genome feature

Region: gene ? Length: 4851  
Location: 22:23834498-23839348 reverse strand Cyto location: 22q11.23

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene Ontology

Gene --> GO terms.



801 SN Ps

5 Cross References

15 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results