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Gene : PLEK2 Homo sapiens

Name  ? pleckstrin 2 Cytological Location  14q23.3-q24.1
Brief Description  pleckstrin 2
description  The protein encoded by this gene associates with membrane-bound phosphatidylinositols generated by phosphatidylinositol 3-kinase. The encoded protein then interacts with the actin cytoskeleton to induce cell spreading. In conjunction with complement component 1, q subcomponent, B chain (C1QB), this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease. [provided by RefSeq, Dec 2015]
  • synonyms:
  • uc001xjh.2,
  • AF228603,
  • NM_016445,
  • PLEK2,
  • HGNC:19238,
  • OTTHUMG00000171247
  • identifiers:
  • 26499,
  • ENSG00000100558,
  • PLEK2

Genome feature

Region: gene ? Length: 25182  
Location: 14:67386984-67412165 reverse strand Cyto location: 14q23.3-q24.1

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Gene Ontology Displayer

0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer

Gene --> Orthologues


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

3756 SN Ps

5 Cross References

16 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results