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Gene : DEFB1 Homo sapiens

Name  ? defensin beta 1 Cytological Location  8p23.1
Brief Description  defensin beta 1
Description  Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008]
  • synonyms:
  • X92744,
  • DEFB-1,
  • BD1,
  • HBD1,
  • DEFB101,
  • uc003wqs.4,
  • beta defensin 1,
  • BD1,
  • HBD-1,
  • DEFB101,
  • beta-defensin 1,
  • OTTHUMG00000090367,
  • HBD1,
  • DEFB-1,
  • MGC51822,
  • defensin, beta 1,
  • DEFB1,
  • NM_005218,
  • HGNC:2766
  • identifiers:
  • 1672,
  • ENSG00000164825,
  • DEFB1

Genome feature

Region: gene ? Length: 7345  
Location: 8:6870592-6877936 reverse strand Cyto location: 8p23.1

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene Ontology

Gene --> GO terms.



3753 SN Ps

5 Cross References

15 Data Sets

18 Homologues

0 Located Features

97 Rna Seq Results