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Gene : FZD8 Homo sapiens

Name  ? frizzled class receptor 8 Cytological Location  10p11.21
Brief Description  frizzled class receptor 8
Description  This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]
  • synonyms:
  • frizzled homolog 8 (Drosophila),
  • NM_031866,
  • AB043703,
  • hFZ8,
  • OTTHUMG00000017956,
  • FZD8,
  • frizzled (Drosophila) homolog 8,
  • FZ-8,
  • frizzled family receptor 8,
  • uc001iyz.2,
  • frizzled 8, seven transmembrane spanning receptor,
  • HGNC:4046
  • identifiers:
  • 8325,
  • ENSG00000177283,
  • FZD8

Genome feature

Region: gene ? Length: 3186  
Location: 10:35638249-35641434 reverse strand Cyto location: 10p11.21

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



380 SN Ps

5 Cross References

16 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results