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Gene : ECT2 Homo sapiens

Name  ? epithelial cell transforming 2 Cytological Location  3q26.31
Brief Description  epithelial cell transforming 2
Description  The protein encoded by this gene is a guanine nucleotide exchange factor and transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]
  • synonyms:
  • OTTHUMG00000156762,
  • ARHGEF31,
  • ECT2,
  • AA206473,
  • epithelial cell transforming sequence 2 oncogene,
  • HGNC:3155,
  • uc003fii.4,
  • ARHGEF31,
  • NM_018098
  • identifiers:
  • 1894,
  • ENSG00000114346,
  • ECT2

Genome feature

Region: gene ? Length: 78589  
Location: 3:172750685-172829273 Cyto location: 3q26.31

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



829 SN Ps

5 Cross References

16 Data Sets

5 Homologues

2 Located Features

97 Rna Seq Results