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Gene : CYP7A1 Homo sapiens

Name  ? cytochrome P450 family 7 subfamily A member 1 Cytological Location  8q12.1
Brief Description  cytochrome P450 family 7 subfamily A member 1
Description  This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis. [provided by RefSeq, Feb 2010]
  • synonyms:
  • OTTHUMG00000164301,
  • M89803,
  • CP7A,
  • HGNC:2651,
  • cholesterol 7 alpha-monooxygenase,
  • CYPVII,
  • uc003xtm.5,
  • CYP7A1,
  • cytochrome P450, family 7, subfamily A, polypeptide 1,
  • cytochrome P450, subfamily VIIA (cholesterol 7 alpha-monooxygenase), polypeptide 1,
  • NM_000780,
  • CYP7,
  • CYP7
  • identifiers:
  • 1581,
  • ENSG00000167910,
  • CYP7A1

Genome feature

Region: gene ? Length: 9986  
Location: 8:58490178-58500163 reverse strand Cyto location: 8q12.1


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Disease

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3753 SN Ps

4 Cross References

15 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results