help  | about  | cite  | software

Gene : CYP3A5 Homo sapiens

Name  ? cytochrome P450 family 3 subfamily A member 5 Cytological Location  7q22.1
Brief Description  cytochrome P450 family 3 subfamily A member 5
Description  This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
  • synonyms:
  • HGNC:2638,
  • CYP3A5,
  • cytochrome P450, family 3, subfamily A, polypeptide 5,
  • PCN3,
  • P450PCN3,
  • CP35,
  • OTTHUMG00000156724,
  • P450PCN3,
  • NM_000777,
  • CP35,
  • PCN3,
  • uc003urq.4,
  • cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5,
  • L26985
  • identifiers:
  • 1577,
  • ENSG00000106258,
  • CYP3A5

Genome feature

Region: gene ? Length: 31803  
Location: 7:99648194-99679996 reverse strand Cyto location: 7q22.1

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3753 SN Ps

5 Cross References

19 Data Sets

17 Homologues

0 Located Features

97 Rna Seq Results