help  | about  | cite  | software

Gene : IGFBP7 Homo sapiens

Name  ? insulin like growth factor binding protein 7 Cytological Location  4q12
Brief Description  insulin like growth factor binding protein 7
Description  This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011]
  • synonyms:
  • IBP-7,
  • FSTL2,
  • IGFBP-7,
  • IGFBP-7v,
  • AGM,
  • MAC25,
  • IGFBP7,
  • PSF,
  • insulin-like growth factor binding protein 7,
  • HGNC:5476,
  • S75725,
  • OTTHUMG00000128772,
  • PSF,
  • IGFBP-7,
  • uc003hcn.4,
  • FSTL2,
  • NM_001253835,
  • TAF,
  • MAC25
  • identifiers:
  • 3490,
  • ENSG00000163453,
  • IGFBP7

Genome feature

Region: gene ? Length: 79613  
Location: 4:57030773-57110385 reverse strand Cyto location: 4q12

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3753 SN Ps

5 Cross References

18 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results