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Gene : CDC23 Homo sapiens

Name  ? cell division cycle 23 Cytological Location  5q31.2
Brief Description  cell division cycle 23
Description  The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq, Jul 2008]
  • synonyms:
  • CDC23,
  • cell division cycle 23 homolog (S. cerevisiae),
  • CUT23,
  • CDC23 (cell division cycle 23, yeast, homolog),
  • ANAPC8,
  • NM_004661,
  • HGNC:1724,
  • OTTHUMG00000129198,
  • APC8,
  • CUT23,
  • APC8,
  • AF053977,
  • ANAPC8,
  • uc003lcl.3,
  • anaphase promoting complex subunit 8
  • identifiers:
  • 8697,
  • ENSG00000094880,
  • CDC23

Genome feature

Region: gene ? Length: 25674  
Location: 5:138187650-138213323 reverse strand Cyto location: 5q31.2


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Function

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45 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

45 Pathways

899 SN Ps

5 Cross References

17 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results