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Gene : EEF1E1 Homo sapiens

Name  ? eukaryotic translation elongation factor 1 epsilon 1 Cytological Location  6p24.3
Brief Description  eukaryotic translation elongation factor 1 epsilon 1
Description  This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2010]
  • synonyms:
  • AIMP3,
  • HGNC:3212,
  • aminoacyl tRNA synthetase complex-interacting multifunctional protein 3,
  • uc003mxz.4,
  • OTTHUMG00000014221,
  • P18,
  • EEF1E1,
  • P18,
  • AF054186,
  • AIMP3,
  • NM_004280
  • identifiers:
  • 9521,
  • ENSG00000124802,
  • EEF1E1

Genome feature

Region: gene ? Length: 29189  
Location: 6:8073360-8102548 reverse strand Cyto location: 6p24.3


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Disease

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890 SN Ps

5 Cross References

15 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results