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Gene : DPH3 Homo sapiens

Name  ? diphthamide biosynthesis 3 Cytological Location  3p25.1
Brief Description  diphthamide biosynthesis 3
Description  This gene encodes a CSL zinc finger-containing protein that is required for dipthamide biosynthesis. The encoded protein is necessary for the initial step in the modification of a histidine residue in elongation factor-2 to diphthamide. This modified residue is a target for ADP ribosylation by the bacterial toxins diphtheria toxin and Pseudomonas exotoxin A. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Feb 2009]
  • synonyms:
  • BC010181,
  • ZCSL2,
  • DPH3 homolog (KTI11, S. cerevisiae),
  • DELGIP1,
  • ZCSL2,
  • HGNC:27717,
  • DPH3,
  • uc003cau.4,
  • MGC20197,
  • DPH3A,
  • NM_206831,
  • DPH3, KTI11 homolog (S. cerevisiae),
  • DPH3A,
  • KTI11,
  • DPH3A, KTI11 homolog A (S. cerevisiae),
  • DESR1,
  • KTI11,
  • DESR1,
  • DELGIP1,
  • OTTHUMG00000129866,
  • zinc finger, CSL-type containing 2
  • identifiers:
  • 285381,
  • ENSG00000154813,
  • DPH3

Genome feature

Region: gene ? Length: 7883  
Location: 3:16257061-16264943 reverse strand Cyto location: 3p25.1

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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3753 SN Ps

5 Cross References

14 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results