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Pathway : Cysteine and methionine metabolism

Identifier  00270 Description  Cysteine and methionine are sulfur-containing amino acids Cysteine is synthesized from serine through different pathways in different organism groups In bacteria and plants, cysteine is converted from serine via acetylserine by transfer of hydrogen sulfide [MD:M00021] In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine cystathionine is converted to cysteine [MD:M00338] Cysteine is metabolized to pyruvate in multiple routes Methionine is an essential amino acid, which animals cannot synthesize In bacteria and plants, methionine is synthesized from aspartate [MD:M00017] S-Adenosylmethionine SAM, synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034]

1 Data Sets

75 Genes

0 Proteins