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Pathway : Spliceosome

Identifier  03040 Description  After transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns In the following splicing, introns are excised and exons are joined by a macromolecular complex, the spliceosome The standard spliceosome is made up of five small nuclear ribonucleoproteins snRNPs, U1, U2, U4, U5, and U6 snRNPs, and several spliceosome-associated proteins SAPs Spliceosomes are not a simple stable complex, but a dynamic family of particles that assemble on the mRNA precursor and help fold it into a conformation that allows transesterification to proceed Various spliceosome forms eg A-, B- and C-complexes have been identified

1 Data Sets

262 Genes

0 Proteins