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Pathway : Sulfur relay system

Identifier  04122 Description  Ubiquitin and ubiquitin-like proteins Ubls are signalling messengers that control many cellular functions, such as cell proliferation, apoptosis, and DNA repair It is suggested that Ub-protein modification evolved from prokaryotic sulfurtransfer systems Molybdenum cofactor Moco and thiamin are sulfur-containing cofactors whose biosynthesis includes a key sulfur transfer step that uses unique sulfur carrier proteins, MoaD and ThiS Ubiquitin, MoaD, and ThiS are all structurally related proteins whose C-termini are activated through adenylation by homologous E1-like enzymes s2T biosynthesis may share similar chemistry with Moco and thiamin synthesis In Saccharomyces cerevisiae, Urm1 and Uba4 function as part of a ubl protein conjugation system, though they have sequence homology to bacterial sulfur-transfer enzymes and the ability to function in sulfur transfer

1 Data Sets

20 Genes

0 Proteins